1s5o
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1s5o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S5O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S5O FirstGlance]. <br> | <table><tr><td colspan='2'>[[1s5o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S5O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1S5O FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=152:CARNITINE'>152</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=152:CARNITINE'>152</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carnitine_O-acetyltransferase Carnitine O-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.7 2.3.1.7] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carnitine_O-acetyltransferase Carnitine O-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.7 2.3.1.7] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s5o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s5o RCSB], [http://www.ebi.ac.uk/pdbsum/1s5o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s5o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1s5o RCSB], [http://www.ebi.ac.uk/pdbsum/1s5o PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CACP_HUMAN CACP_HUMAN]] Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Carnitine O-acetyltransferase]] | [[Category: Carnitine O-acetyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Agbandje-Mckenna, M | + | [[Category: Agbandje-Mckenna, M]] |
| - | [[Category: Govindasamy, L | + | [[Category: Govindasamy, L]] |
| - | [[Category: Gu, Y | + | [[Category: Gu, Y]] |
| - | [[Category: Jin, S | + | [[Category: Jin, S]] |
| - | [[Category: Kukar, T | + | [[Category: Kukar, T]] |
| - | [[Category: Lian, W | + | [[Category: Lian, W]] |
| - | [[Category: Mckenna, R | + | [[Category: Mckenna, R]] |
| - | [[Category: Pedersen, B | + | [[Category: Pedersen, B]] |
| - | [[Category: Wu, D | + | [[Category: Wu, D]] |
[[Category: Binary complex]] | [[Category: Binary complex]] | ||
[[Category: Carnitine acetyltransferase]] | [[Category: Carnitine acetyltransferase]] | ||
Revision as of 05:58, 25 December 2014
Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase
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