1imv
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1imv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IMV FirstGlance]. <br> | <table><tr><td colspan='2'>[[1imv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IMV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1imv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1imv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1imv RCSB], [http://www.ebi.ac.uk/pdbsum/1imv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1imv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1imv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1imv RCSB], [http://www.ebi.ac.uk/pdbsum/1imv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/PEDF_HUMAN PEDF_HUMAN]] Defects in SERPINF1 are the cause of osteogenesis imperfecta type 12 (OI12) [MIM:[http://omim.org/entry/613982 613982]]. OI12 is a connective tissue disorder characterized by bone fragility, low bone mass, and recurrent fractures. OI12 is characterized by features compatible with osteogenesis imperfecta type III in the Sillence classification. Patients have normal grayish sclerae and fractures of long bones and severe vertebral compression fractures, with resulting deformities observed as early as the first year of life.<ref>PMID:21353196</ref> | [[http://www.uniprot.org/uniprot/PEDF_HUMAN PEDF_HUMAN]] Defects in SERPINF1 are the cause of osteogenesis imperfecta type 12 (OI12) [MIM:[http://omim.org/entry/613982 613982]]. OI12 is a connective tissue disorder characterized by bone fragility, low bone mass, and recurrent fractures. OI12 is characterized by features compatible with osteogenesis imperfecta type III in the Sillence classification. Patients have normal grayish sclerae and fractures of long bones and severe vertebral compression fractures, with resulting deformities observed as early as the first year of life.<ref>PMID:21353196</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Gettins, P G.W | + | [[Category: Gettins, P G.W]] |
| - | [[Category: Simonovic, M | + | [[Category: Simonovic, M]] |
| - | [[Category: Volz, K | + | [[Category: Volz, K]] |
[[Category: Angiogenesis]] | [[Category: Angiogenesis]] | ||
[[Category: Pedf]] | [[Category: Pedf]] | ||
[[Category: Serpin]] | [[Category: Serpin]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 09:50, 2 January 2015
2.85 A crystal structure of PEDF
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