1ips

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ips]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IPS FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ips]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IPS FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PCB C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=162425 Emericella nidulans])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PCB C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=162425 Emericella nidulans])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ips FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ips OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ips RCSB], [http://www.ebi.ac.uk/pdbsum/1ips PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ips FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ips OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ips RCSB], [http://www.ebi.ac.uk/pdbsum/1ips PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IPNS_EMENI IPNS_EMENI]] Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Emericella nidulans]]
[[Category: Emericella nidulans]]
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[[Category: Andersson, I.]]
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[[Category: Andersson, I]]
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[[Category: Baldwin, J E.]]
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[[Category: Baldwin, J E]]
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[[Category: Barton, G J.]]
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[[Category: Barton, G J]]
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[[Category: Clifton, I J.]]
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[[Category: Clifton, I J]]
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[[Category: Fulop, V.]]
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[[Category: Fulop, V]]
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[[Category: Hajdu, J.]]
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[[Category: Hajdu, J]]
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[[Category: Harlos, K.]]
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[[Category: Harlos, K]]
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[[Category: Roach, P L.]]
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[[Category: Roach, P L]]
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[[Category: Schofield, C J.]]
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[[Category: Schofield, C J]]
[[Category: Antibiotic biosynthesis]]
[[Category: Antibiotic biosynthesis]]
[[Category: B-lactam antibiotic]]
[[Category: B-lactam antibiotic]]

Revision as of 21:40, 24 December 2014

ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX)

1ips, resolution 2.50Å

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