1ic2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ic2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IC2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ic2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IC2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ic2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ic2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ic2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ic2 PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ic2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ic2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ic2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ic2 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TPM1_CHICK TPM1_CHICK]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Brown, J H.]]
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[[Category: Brown, J H]]
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[[Category: Cohen, C.]]
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[[Category: Cohen, C]]
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[[Category: Dominguez, R.]]
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[[Category: Dominguez, R]]
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[[Category: Greenfield, N J.]]
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[[Category: Greenfield, N J]]
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[[Category: Hitchcock-DeGregori, S E.]]
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[[Category: Hitchcock-DeGregori, S E]]
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[[Category: Jun, G.]]
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[[Category: Jun, G]]
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[[Category: Kim, K H.]]
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[[Category: Kim, K H]]
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[[Category: Volkmann, N.]]
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[[Category: Volkmann, N]]
[[Category: Alanine]]
[[Category: Alanine]]
[[Category: Alpha-helical coiled coil]]
[[Category: Alpha-helical coiled coil]]

Revision as of 10:48, 25 December 2014

DECIPHERING THE DESIGN OF THE TROPOMYOSIN MOLECULE

1ic2, resolution 2.00Å

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