1ujx

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ujx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UJX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ujx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UJX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 1810009G08 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 1810009G08 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ujx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ujx RCSB], [http://www.ebi.ac.uk/pdbsum/1ujx PDBsum], [http://www.topsan.org/Proteins/RSGI/1ujx TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ujx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ujx RCSB], [http://www.ebi.ac.uk/pdbsum/1ujx PDBsum], [http://www.topsan.org/Proteins/RSGI/1ujx TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PNKP_MOUSE PNKP_MOUSE]] Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba, S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Tomizawa, T.]]
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[[Category: Tomizawa, T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Antiparallel beta-sheet]]
[[Category: Antiparallel beta-sheet]]
[[Category: Beta-sandwich]]
[[Category: Beta-sandwich]]
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[[Category: Phosphopeptide binding motif]]
[[Category: Phosphopeptide binding motif]]
[[Category: Polynucleotide kinase 3'-phosphatase]]
[[Category: Polynucleotide kinase 3'-phosphatase]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 17:59, 24 December 2014

The forkhead associated (FHA) domain like structure from mouse polynucleotide kinase 3'-phosphatase

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