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1unb
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1unb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UNB FirstGlance]. <br> | <table><tr><td colspan='2'>[[1unb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UNB FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=PN1:(2S,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>PN1</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=PN1:(2S,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>PN1</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dcs|1dcs]], [[1e5h|1e5h]], [[1e5i|1e5i]], [[1hjf|1hjf]], [[1hjg|1hjg]], [[1rxf|1rxf]], [[1rxg|1rxg]], [[1uo9|1uo9]], [[1uob|1uob]], [[1uof|1uof]], [[1uog|1uog]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dcs|1dcs]], [[1e5h|1e5h]], [[1e5i|1e5i]], [[1hjf|1hjf]], [[1hjg|1hjg]], [[1rxf|1rxf]], [[1rxg|1rxg]], [[1uo9|1uo9]], [[1uob|1uob]], [[1uof|1uof]], [[1uog|1uog]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deacetoxycephalosporin-C_synthase Deacetoxycephalosporin-C synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.20.1 1.14.20.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deacetoxycephalosporin-C_synthase Deacetoxycephalosporin-C synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.20.1 1.14.20.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1unb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1unb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1unb RCSB], [http://www.ebi.ac.uk/pdbsum/1unb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1unb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1unb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1unb RCSB], [http://www.ebi.ac.uk/pdbsum/1unb PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CEFE_STRCL CEFE_STRCL]] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Deacetoxycephalosporin-C synthase]] | [[Category: Deacetoxycephalosporin-C synthase]] | ||
[[Category: Streptomyces clavuligerus]] | [[Category: Streptomyces clavuligerus]] | ||
| - | [[Category: Andersson, I | + | [[Category: Andersson, I]] |
| - | [[Category: Dubus, A | + | [[Category: Dubus, A]] |
| - | [[Category: Hajdu, J | + | [[Category: Hajdu, J]] |
| - | [[Category: Oster, L M | + | [[Category: Oster, L M]] |
| - | [[Category: Rhangino, G | + | [[Category: Rhangino, G]] |
| - | [[Category: Scheltinga, A C.Terwisscha Van | + | [[Category: Scheltinga, A C.Terwisscha Van]] |
| - | [[Category: Valegard, K | + | [[Category: Valegard, K]] |
[[Category: Antibiotic biosynthesis]] | [[Category: Antibiotic biosynthesis]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 07:32, 25 December 2014
DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH 2-OXOGLUTARATE AND AMPICILLIN
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