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1u65
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1u65]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U65 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U65 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1u65]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U65 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U65 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CP0:(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3,4 6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL+1,4-BIPIPERIDINE-1-CARBOXYLATE'>CP0</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CP0:(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3,4 6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL+1,4-BIPIPERIDINE-1-CARBOXYLATE'>CP0</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u65 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u65 RCSB], [http://www.ebi.ac.uk/pdbsum/1u65 PDBsum], [http://www.topsan.org/Proteins/ISPC/1u65 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u65 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u65 RCSB], [http://www.ebi.ac.uk/pdbsum/1u65 PDBsum], [http://www.topsan.org/Proteins/ISPC/1u65 TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
[[Category: Torpedo californica]] | [[Category: Torpedo californica]] | ||
| - | [[Category: Brumshtein, B | + | [[Category: Brumshtein, B]] |
| - | [[Category: Harel, M | + | [[Category: Harel, M]] |
| - | [[Category: Hyatt, J L | + | [[Category: Hyatt, J L]] |
| - | [[Category: ISPC, Israel Structural Proteomics Center | + | [[Category: ISPC, Israel Structural Proteomics Center]] |
| - | [[Category: Morton, C L | + | [[Category: Morton, C L]] |
| - | [[Category: Potter, P M | + | [[Category: Potter, P M]] |
| - | [[Category: Silman, I | + | [[Category: Silman, I]] |
| - | [[Category: Sussman, J L | + | [[Category: Sussman, J L]] |
| - | [[Category: Wadkins, R W | + | [[Category: Wadkins, R W]] |
[[Category: Anticancer prodrug cpt-11]] | [[Category: Anticancer prodrug cpt-11]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: ISPC]] | ||
| - | [[Category: Israel Structural Proteomics Center]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Torpedo ache]] | [[Category: Torpedo ache]] | ||
Revision as of 04:34, 24 November 2014
Ache W. CPT-11
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