This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1t56
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1t56]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T56 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1t56]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T56 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t56 RCSB], [http://www.ebi.ac.uk/pdbsum/1t56 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t56 RCSB], [http://www.ebi.ac.uk/pdbsum/1t56 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/P96222_MYCTU P96222_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 29: | Line 31: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Besra, G S | + | [[Category: Besra, G S]] |
| - | [[Category: Cocklin, S L | + | [[Category: Cocklin, S L]] |
| - | [[Category: Corsino, P E | + | [[Category: Corsino, P E]] |
| - | [[Category: Daniels, I R | + | [[Category: Daniels, I R]] |
| - | [[Category: Dover, L G | + | [[Category: Dover, L G]] |
| - | [[Category: Futterer, K | + | [[Category: Futterer, K]] |
| - | [[Category: Tatituri, V | + | [[Category: Tatituri, V]] |
[[Category: Dimer]] | [[Category: Dimer]] | ||
[[Category: Helix-turn-helix]] | [[Category: Helix-turn-helix]] | ||
[[Category: Tetr family]] | [[Category: Tetr family]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 18:25, 24 December 2014
Crystal structure of TetR family repressor M. tuberculosis EthR
| |||||||||||
