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1w30
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1w30]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W30 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1w30]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W30 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uracil_phosphoribosyltransferase Uracil phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.9 2.4.2.9] </span></td></tr> | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uracil_phosphoribosyltransferase Uracil phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.9 2.4.2.9] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w30 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w30 RCSB], [http://www.ebi.ac.uk/pdbsum/1w30 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w30 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w30 RCSB], [http://www.ebi.ac.uk/pdbsum/1w30 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PYRR_MYCTU PYRR_MYCTU]] Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines (By similarity). Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Uracil phosphoribosyltransferase]] | [[Category: Uracil phosphoribosyltransferase]] | ||
| - | [[Category: Castro, P | + | [[Category: Castro, P]] |
| - | [[Category: Kantardjieff, K A | + | [[Category: Kantardjieff, K A]] |
| - | [[Category: Kim, C Y | + | [[Category: Kim, C Y]] |
| - | [[Category: Lekin, T | + | [[Category: Lekin, T]] |
| - | [[Category: Rho, B S | + | [[Category: Rho, B S]] |
| - | [[Category: Rupp, B | + | [[Category: Rupp, B]] |
| - | [[Category: Segelke, B W | + | [[Category: Segelke, B W]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Terwilliger, T | + | [[Category: Terwilliger, T]] |
| - | [[Category: Vasquez, C | + | [[Category: Vasquez, C]] |
| - | [[Category: Warfel, N N | + | [[Category: Warfel, N N]] |
[[Category: Glycosyltransferase]] | [[Category: Glycosyltransferase]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Pyrr]] | [[Category: Pyrr]] | ||
[[Category: Tb]] | [[Category: Tb]] | ||
| - | [[Category: Tb structural genomics consortium]] | ||
[[Category: Tbsgc]] | [[Category: Tbsgc]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 03:37, 25 December 2014
PYRR OF MYCOBACTERIUM TUBERCULOSIS AS A POTENTIAL DRUG TARGET
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Categories: Mycobacterium tuberculosis | Uracil phosphoribosyltransferase | Castro, P | Kantardjieff, K A | Kim, C Y | Lekin, T | Rho, B S | Rupp, B | Segelke, B W | Structural genomic | Terwilliger, T | Vasquez, C | Warfel, N N | Glycosyltransferase | PSI, Protein structure initiative | Pyrr | Tb | Tbsgc | Transferase
