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1xzq

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xzq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xzq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZQ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FON:N-{[4-({[(6R)-2-AMINO-5-FORMYL-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)PHENYL]CARBONYL}-L-GLUTAMIC+ACID'>FON</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FON:N-{[4-({[(6R)-2-AMINO-5-FORMYL-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)PHENYL]CARBONYL}-L-GLUTAMIC+ACID'>FON</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xzp|1xzp]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xzp|1xzp]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TrmE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TrmE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzq RCSB], [http://www.ebi.ac.uk/pdbsum/1xzq PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzq RCSB], [http://www.ebi.ac.uk/pdbsum/1xzq PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TRME_THEMA TRME_THEMA]] Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.[HAMAP-Rule:MF_00379]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Armengod, M E.]]
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[[Category: Armengod, M E]]
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[[Category: Scrima, A.]]
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[[Category: Scrima, A]]
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[[Category: Vetter, I R.]]
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[[Category: Vetter, I R]]
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[[Category: Wittinghofer, A.]]
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[[Category: Wittinghofer, A]]
[[Category: Gtp-binding]]
[[Category: Gtp-binding]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Thf-binding]]
[[Category: Thf-binding]]
[[Category: Trna-modification]]
[[Category: Trna-modification]]

Revision as of 07:57, 25 December 2014

Structure of the GTP-binding protein TrmE from Thermotoga maritima complexed with 5-formyl-THF

1xzq, resolution 2.90Å

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