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1wxr
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1wxr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXR FirstGlance]. <br> | <table><tr><td colspan='2'>[[1wxr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXR FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wxr RCSB], [http://www.ebi.ac.uk/pdbsum/1wxr PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wxr RCSB], [http://www.ebi.ac.uk/pdbsum/1wxr PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HBP_ECOLX HBP_ECOLX]] Interacts with hemoglobin, degrades it and subsequently binds the released heme. Could make heme accessible not only for E.coli, but also for B.fragilis during mixed intra-abdominal infections. Has a role in abscess formation.<ref>PMID:9743528</ref> <ref>PMID:11748157</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Heddle, J G | + | [[Category: Heddle, J G]] |
| - | [[Category: Luirink, J | + | [[Category: Luirink, J]] |
| - | [[Category: Mizutani, K | + | [[Category: Mizutani, K]] |
| - | [[Category: Otto, B R | + | [[Category: Otto, B R]] |
| - | [[Category: Oudega, B | + | [[Category: Oudega, B]] |
| - | [[Category: Park, S Y | + | [[Category: Park, S Y]] |
| - | [[Category: Sijbrandi, R | + | [[Category: Sijbrandi, R]] |
| - | [[Category: Tame, J R.H | + | [[Category: Tame, J R.H]] |
[[Category: Autotransporter]] | [[Category: Autotransporter]] | ||
[[Category: Beta helix]] | [[Category: Beta helix]] | ||
Revision as of 18:32, 24 December 2014
Crystal structure of Heme Binding protein, an autotransporter hemoglobine protease from pathogenic Escherichia coli
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