1yty

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1yty]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YTY FirstGlance]. <br>
<table><tr><td colspan='2'>[[1yty]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YTY FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SSB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SSB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yty OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yty RCSB], [http://www.ebi.ac.uk/pdbsum/1yty PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yty OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yty RCSB], [http://www.ebi.ac.uk/pdbsum/1yty PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LA_HUMAN LA_HUMAN]] Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.<ref>PMID:3192525</ref> <ref>PMID:2470590</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ilin, S.]]
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[[Category: Ilin, S]]
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[[Category: Malinina, L.]]
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[[Category: Malinina, L]]
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[[Category: Patel, D J.]]
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[[Category: Patel, D J]]
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[[Category: Phan, A T.]]
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[[Category: Phan, A T]]
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[[Category: Teplov, A.]]
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[[Category: Teplov, A]]
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[[Category: Teplova, M.]]
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[[Category: Teplova, M]]
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[[Category: Yuan, Y R.]]
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[[Category: Yuan, Y R]]
[[Category: Protein-rna complex]]
[[Category: Protein-rna complex]]
[[Category: Transcription-rna complex]]
[[Category: Transcription-rna complex]]

Revision as of 08:20, 25 December 2014

Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen

1yty, resolution 2.29Å

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