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1ugy

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ugy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UGY FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ugy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UGY FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m26|1m26]], [[1jac|1jac]], [[1ugw|1ugw]], [[1ugx|1ugx]], [[1uh0|1uh0]], [[1uh1|1uh1]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m26|1m26]], [[1jac|1jac]], [[1ugw|1ugw]], [[1ugx|1ugx]], [[1uh0|1uh0]], [[1uh1|1uh1]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ugy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ugy RCSB], [http://www.ebi.ac.uk/pdbsum/1ugy PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ugy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ugy RCSB], [http://www.ebi.ac.uk/pdbsum/1ugy PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Artocarpus integer]]
[[Category: Artocarpus integer]]
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[[Category: Jeyaprakash, A A.]]
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[[Category: Jeyaprakash, A A]]
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[[Category: Katiyar, S.]]
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[[Category: Katiyar, S]]
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[[Category: Sekar, K.]]
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[[Category: Sekar, K]]
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[[Category: Surolia, A.]]
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[[Category: Surolia, A]]
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[[Category: Swaminathan, C P.]]
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[[Category: Swaminathan, C P]]
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[[Category: Vijayan, M.]]
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[[Category: Vijayan, M]]
[[Category: All beta sheets protein]]
[[Category: All beta sheets protein]]
[[Category: Beta-prism i fold]]
[[Category: Beta-prism i fold]]
[[Category: Gal specific]]
[[Category: Gal specific]]
[[Category: Sugar binding protein]]
[[Category: Sugar binding protein]]

Revision as of 12:33, 25 December 2014

Crystal structure of jacalin- mellibiose (Gal-alpha(1-6)-Glc) complex

1ugy, resolution 2.40Å

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