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1wrp
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1wrp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRP FirstGlance]. <br> | <table><tr><td colspan='2'>[[1wrp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WRP FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wrp|3wrp]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wrp|3wrp]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wrp RCSB], [http://www.ebi.ac.uk/pdbsum/1wrp PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wrp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wrp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wrp RCSB], [http://www.ebi.ac.uk/pdbsum/1wrp PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Joachimiak, A J | + | [[Category: Joachimiak, A J]] |
| - | [[Category: Lawson, C L | + | [[Category: Lawson, C L]] |
| - | [[Category: Otwinowski, Z | + | [[Category: Otwinowski, Z]] |
| - | [[Category: Schewitz, R W | + | [[Category: Schewitz, R W]] |
| - | [[Category: Sigler, P B | + | [[Category: Sigler, P B]] |
[[Category: Dna binding regulatory protein]] | [[Category: Dna binding regulatory protein]] | ||
Revision as of 13:37, 24 December 2014
FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR
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