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1t9b

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1t9b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T9B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T9B FirstGlance]. <br>
<table><tr><td colspan='2'>[[1t9b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T9B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T9B FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1CS:1-(2-CHLOROPHENYLSULFONYL)-3-(4-METHOXY-6-METHYL-L,3,5-TRIAZIN-2-YL)UREA'>1CS</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NSP:5-(AMINOMETHYL)-2-METHYLPYRIMIDIN-4-AMINE'>NSP</scene>, <scene name='pdbligand=P22:ETHYL+DIHYDROGEN+DIPHOSPHATE'>P22</scene>, <scene name='pdbligand=P25:PENTYL+TRIHYDROGEN+DIPHOSPHATE'>P25</scene>, <scene name='pdbligand=YF3:2-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}PROPANE-1-THIOL'>YF3</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1CS:1-(2-CHLOROPHENYLSULFONYL)-3-(4-METHOXY-6-METHYL-L,3,5-TRIAZIN-2-YL)UREA'>1CS</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NSP:5-(AMINOMETHYL)-2-METHYLPYRIMIDIN-4-AMINE'>NSP</scene>, <scene name='pdbligand=P22:ETHYL+DIHYDROGEN+DIPHOSPHATE'>P22</scene>, <scene name='pdbligand=P25:PENTYL+TRIHYDROGEN+DIPHOSPHATE'>P25</scene>, <scene name='pdbligand=YF3:2-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}PROPANE-1-THIOL'>YF3</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1n0h|1n0h]], [[1t9c|1t9c]], [[1t9d|1t9d]], [[1t9a|1t9a]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1n0h|1n0h]], [[1t9c|1t9c]], [[1t9d|1t9d]], [[1t9a|1t9a]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ILV2, SMR1, YMR108W, YM9718.07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ILV2, SMR1, YMR108W, YM9718.07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t9b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t9b RCSB], [http://www.ebi.ac.uk/pdbsum/1t9b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t9b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t9b RCSB], [http://www.ebi.ac.uk/pdbsum/1t9b PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Acetolactate synthase]]
[[Category: Acetolactate synthase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Duggleby, R G.]]
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[[Category: Duggleby, R G]]
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[[Category: Guddat, L W.]]
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[[Category: Guddat, L W]]
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[[Category: McCourt, J A.]]
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[[Category: McCourt, J A]]
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[[Category: Pang, S S.]]
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[[Category: Pang, S S]]
[[Category: Acetohydroxyacid synthase]]
[[Category: Acetohydroxyacid synthase]]
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[[Category: Acetolactate synthase]]
 
[[Category: Chlorsulfuron]]
[[Category: Chlorsulfuron]]
[[Category: Fad]]
[[Category: Fad]]

Revision as of 07:45, 6 January 2015

Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron

1t9b, resolution 2.20Å

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