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1uu8
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1uu8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UU8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UU8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1uu8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UU8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UU8 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BI1:3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE'>BI1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BI1:3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE'>BI1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h1w|1h1w]], [[1oky|1oky]], [[1okz|1okz]], [[1uu3|1uu3]], [[1uu7|1uu7]], [[1uu9|1uu9]], [[1uvr|1uvr]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h1w|1h1w]], [[1oky|1oky]], [[1okz|1okz]], [[1uu3|1uu3]], [[1uu7|1uu7]], [[1uu9|1uu9]], [[1uvr|1uvr]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uu8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uu8 RCSB], [http://www.ebi.ac.uk/pdbsum/1uu8 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uu8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uu8 RCSB], [http://www.ebi.ac.uk/pdbsum/1uu8 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 36: | Line 36: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Aalten, D M.F Van | + | [[Category: Aalten, D M.F Van]] |
| - | [[Category: Alessi, D R | + | [[Category: Alessi, D R]] |
| - | [[Category: Bain, J | + | [[Category: Bain, J]] |
| - | [[Category: Deak, M | + | [[Category: Deak, M]] |
| - | [[Category: Elliot, M | + | [[Category: Elliot, M]] |
| - | [[Category: Garrido-Franco, M | + | [[Category: Garrido-Franco, M]] |
| - | [[Category: Komander, D | + | [[Category: Komander, D]] |
| - | [[Category: Kozikowski, A P | + | [[Category: Kozikowski, A P]] |
| - | [[Category: Kular, G S | + | [[Category: Kular, G S]] |
| - | [[Category: Prakash, K R | + | [[Category: Prakash, K R]] |
| - | [[Category: Schuttelkopf, A W | + | [[Category: Schuttelkopf, A W]] |
[[Category: Bim-1]] | [[Category: Bim-1]] | ||
[[Category: Bisindolyl maleimide]] | [[Category: Bisindolyl maleimide]] | ||
Revision as of 13:25, 6 January 2015
STRUCTURE OF HUMAN PDK1 KINASE DOMAIN IN COMPLEX WITH BIM-1
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Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Aalten, D M.F Van | Alessi, D R | Bain, J | Deak, M | Elliot, M | Garrido-Franco, M | Komander, D | Kozikowski, A P | Kular, G S | Prakash, K R | Schuttelkopf, A W | Bim-1 | Bisindolyl maleimide | Cancer | Diabetes | Inhibitor | Ly333531 | Pdk1 | Pkb | Protein kinase | Serine/threonine-protein kinase | Transferase
