1v3y
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1v3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3Y FirstGlance]. <br> | <table><tr><td colspan='2'>[[1v3y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3Y FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3y RCSB], [http://www.ebi.ac.uk/pdbsum/1v3y PDBsum], [http://www.topsan.org/Proteins/RSGI/1v3y TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3y RCSB], [http://www.ebi.ac.uk/pdbsum/1v3y PDBsum], [http://www.topsan.org/Proteins/RSGI/1v3y TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DEF_THETH DEF_THETH]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Peptide deformylase]] | [[Category: Peptide deformylase]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Ito, K | + | [[Category: Ito, K]] |
| - | [[Category: Kamo, M | + | [[Category: Kamo, M]] |
| - | [[Category: Kudo, N | + | [[Category: Kudo, N]] |
| - | [[Category: Lee, W C | + | [[Category: Lee, W C]] |
| - | [[Category: Motoshim, H | + | [[Category: Motoshim, H]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Tanokura, M | + | [[Category: Tanokura, M]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| - | [[Category: Peptide deformylase]] | ||
[[Category: Protein synthesis]] | [[Category: Protein synthesis]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 00:28, 25 December 2014
The crystal structure of peptide deformylase from Thermus thermophilus HB8
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