7ahl
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7ahl]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7AHL FirstGlance]. <br> | <table><tr><td colspan='2'>[[7ahl]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7AHL FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7ahl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ahl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=7ahl RCSB], [http://www.ebi.ac.uk/pdbsum/7ahl PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7ahl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ahl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=7ahl RCSB], [http://www.ebi.ac.uk/pdbsum/7ahl PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HLA_STAAU HLA_STAAU]] Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Bayley, H | + | [[Category: Bayley, H]] |
| - | [[Category: Cheley, S | + | [[Category: Cheley, S]] |
| - | [[Category: Gouaux, J E | + | [[Category: Gouaux, J E]] |
| - | [[Category: Hobaugh, M | + | [[Category: Hobaugh, M]] |
| - | [[Category: Shustak, C | + | [[Category: Shustak, C]] |
| - | [[Category: Song, L | + | [[Category: Song, L]] |
[[Category: Cytolytic protein]] | [[Category: Cytolytic protein]] | ||
[[Category: Hemolysin]] | [[Category: Hemolysin]] | ||
[[Category: Transmembrane pore]] | [[Category: Transmembrane pore]] | ||
Revision as of 14:13, 24 December 2014
ALPHA-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS
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