1xkp

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xkp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKP FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xkp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKP FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMG:N,N-DIMETHYLGLYCINE'>DMG</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMG:N,N-DIMETHYLGLYCINE'>DMG</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yopN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis]), sycN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis]), yscB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yopN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis]), sycN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis]), yscB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkp RCSB], [http://www.ebi.ac.uk/pdbsum/1xkp PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkp RCSB], [http://www.ebi.ac.uk/pdbsum/1xkp PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/YSCB_YERPE YSCB_YERPE]] Functions as a specific chaperone for YopN. It could facilitate the secretion and the subsequent translocation of YopN.<ref>PMID:9733695</ref> <ref>PMID:10094626</ref> <ref>PMID:12535078</ref> [[http://www.uniprot.org/uniprot/SYCN_YERPE SYCN_YERPE]] Functions as a specific chaperone for YopN. It could facilitate the secretion and the subsequent translocation of YopN.<ref>PMID:10094626</ref> <ref>PMID:12535078</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Yersinia pestis]]
[[Category: Yersinia pestis]]
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[[Category: Cherry, S.]]
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[[Category: Cherry, S]]
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[[Category: Jackson, M W.]]
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[[Category: Jackson, M W]]
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[[Category: Penrose, K J.]]
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[[Category: Penrose, K J]]
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[[Category: Plano, G V.]]
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[[Category: Plano, G V]]
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[[Category: Schubot, F D.]]
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[[Category: Schubot, F D]]
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[[Category: Tropea, J E.]]
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[[Category: Tropea, J E]]
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[[Category: Waugh, D S.]]
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[[Category: Waugh, D S]]
[[Category: Chaperone]]
[[Category: Chaperone]]
[[Category: Membrane protein-chaperon complex]]
[[Category: Membrane protein-chaperon complex]]

Revision as of 21:12, 25 December 2014

Crystal structure of the virulence factor YopN in complex with its heterodimeric chaperone SycN-YscB

1xkp, resolution 1.70Å

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