1z60
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1z60]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1e53 1e53]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z60 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1z60]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1e53 1e53]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z60 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z60 RCSB], [http://www.ebi.ac.uk/pdbsum/1z60 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z60 RCSB], [http://www.ebi.ac.uk/pdbsum/1z60 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TF2H2_HUMAN TF2H2_HUMAN]] Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Boelens, R | + | [[Category: Boelens, R]] |
| - | [[Category: Dominguez, C | + | [[Category: Dominguez, C]] |
| - | [[Category: Fribourg, S | + | [[Category: Fribourg, S]] |
| - | [[Category: Kellenberger, E | + | [[Category: Kellenberger, E]] |
| - | [[Category: Kieffer, B | + | [[Category: Kieffer, B]] |
| - | [[Category: Moras, D | + | [[Category: Moras, D]] |
| - | [[Category: Poterszman, A | + | [[Category: Poterszman, A]] |
| - | [[Category: Wasielewski, E | + | [[Category: Wasielewski, E]] |
[[Category: Basic transcription factor]] | [[Category: Basic transcription factor]] | ||
[[Category: Ring finger]] | [[Category: Ring finger]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Zinc binding protein]] | [[Category: Zinc binding protein]] | ||
Revision as of 20:24, 24 December 2014
Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit
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