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1z0u
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1z0u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z0U FirstGlance]. <br> | <table><tr><td colspan='2'>[[1z0u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z0U FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ppnK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2234 Archaeoglobus fulgidus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ppnK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2234 Archaeoglobus fulgidus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_kinase NAD(+) kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.23 2.7.1.23] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_kinase NAD(+) kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.23 2.7.1.23] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z0u RCSB], [http://www.ebi.ac.uk/pdbsum/1z0u PDBsum], [http://www.topsan.org/Proteins/BSGC/1z0u TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z0u RCSB], [http://www.ebi.ac.uk/pdbsum/1z0u PDBsum], [http://www.topsan.org/Proteins/BSGC/1z0u TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PPNK_ARCFU PPNK_ARCFU]] Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.<ref>PMID:16242716</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Archaeoglobus fulgidus]] | [[Category: Archaeoglobus fulgidus]] | ||
| - | [[Category: Adams, P D | + | [[Category: Adams, P D]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Kim, R | + | [[Category: Kim, R]] |
| - | [[Category: Kim, S H | + | [[Category: Kim, S H]] |
| - | [[Category: Liu, J | + | [[Category: Liu, J]] |
| - | [[Category: Lou, Y | + | [[Category: Lou, Y]] |
| - | [[Category: Yokota, H | + | [[Category: Yokota, H]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
| - | [[Category: Berkeley structural genomics center]] | ||
[[Category: Bsgc]] | [[Category: Bsgc]] | ||
[[Category: Nad]] | [[Category: Nad]] | ||
[[Category: Nad kinase]] | [[Category: Nad kinase]] | ||
[[Category: Nadp]] | [[Category: Nadp]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
| - | + | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 15:08, 24 December 2014
Crystal structure of a NAD kinase from Archaeoglobus fulgidus bound by NADP
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Categories: Archaeoglobus fulgidus | Adams, P D | Structural genomic | Kim, R | Kim, S H | Liu, J | Lou, Y | Yokota, H | Atp-binding | Bsgc | Nad | Nad kinase | Nadp | PSI, Protein structure initiative | Transferase
