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1xa6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xa6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XA6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xa6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XA6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xa6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xa6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xa6 RCSB], [http://www.ebi.ac.uk/pdbsum/1xa6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xa6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xa6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xa6 RCSB], [http://www.ebi.ac.uk/pdbsum/1xa6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CHIO_HUMAN CHIO_HUMAN]] GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Canagarajah, B | + | [[Category: Canagarajah, B]] |
| - | [[Category: Ho, J Y | + | [[Category: Ho, J Y]] |
| - | [[Category: Hurley, J H | + | [[Category: Hurley, J H]] |
| - | [[Category: Kazanietz, M G | + | [[Category: Kazanietz, M G]] |
| - | [[Category: Leskow, F C | + | [[Category: Leskow, F C]] |
| - | [[Category: Mischak, H | + | [[Category: Mischak, H]] |
| - | [[Category: Saidi, L F | + | [[Category: Saidi, L F]] |
[[Category: Beta2-chimaerin]] | [[Category: Beta2-chimaerin]] | ||
[[Category: C1]] | [[Category: C1]] | ||
[[Category: Racgap]] | [[Category: Racgap]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 15:16, 24 December 2014
Crystal Structure of the Human Beta2-Chimaerin
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Categories: Homo sapiens | Canagarajah, B | Ho, J Y | Hurley, J H | Kazanietz, M G | Leskow, F C | Mischak, H | Saidi, L F | Beta2-chimaerin | C1 | Racgap | Signaling protein
