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1wvr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wvr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WVR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WVR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wvr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WVR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WVR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wvr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wvr RCSB], [http://www.ebi.ac.uk/pdbsum/1wvr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wvr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wvr RCSB], [http://www.ebi.ac.uk/pdbsum/1wvr PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CRVP_TRIFL CRVP_TRIFL]] Blocks contraction of smooth muscle elicited by high potassium-induced depolarization (PubMed:12047379). May target voltage-gated calcium channels (Cav) on smooth muscle.<ref>PMID:12047379</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Trimeresurus flavoviridis]]
[[Category: Trimeresurus flavoviridis]]
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[[Category: Mizuno, H.]]
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[[Category: Mizuno, H]]
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[[Category: Morita, T.]]
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[[Category: Morita, T]]
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[[Category: Shikamoto, Y.]]
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[[Category: Shikamoto, Y]]
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[[Category: Suto, K.]]
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[[Category: Suto, K]]
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[[Category: Yamazaki, Y.]]
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[[Category: Yamazaki, Y]]
[[Category: Cysteine-rich secretory protein]]
[[Category: Cysteine-rich secretory protein]]
[[Category: Toxin]]
[[Category: Toxin]]

Revision as of 14:00, 25 December 2014

Crystal Structure of a CRISP family Ca-channel blocker derived from snake venom

1wvr, resolution 2.40Å

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