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1u34
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1u34]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U34 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U34 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1u34]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U34 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U34 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u34 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u34 RCSB], [http://www.ebi.ac.uk/pdbsum/1u34 PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u34 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u34 RCSB], [http://www.ebi.ac.uk/pdbsum/1u34 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CRFR2_MOUSE CRFR2_MOUSE]] This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: DiGruccio, M R | + | [[Category: DiGruccio, M R]] |
| - | [[Category: Grace, C R | + | [[Category: Grace, C R]] |
| - | [[Category: Miller, C L | + | [[Category: Miller, C L]] |
| - | [[Category: Perrin, M H | + | [[Category: Perrin, M H]] |
| - | [[Category: Riek, R | + | [[Category: Riek, R]] |
| - | [[Category: Rivier, J E | + | [[Category: Rivier, J E]] |
| - | [[Category: Vale, W W | + | [[Category: Vale, W W]] |
[[Category: Beta sheets and loop]] | [[Category: Beta sheets and loop]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 15:42, 24 December 2014
3D NMR structure of the first extracellular domain of CRFR-2beta, a type B1 G-protein coupled receptor
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