1uuv

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uuv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UUV FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uuv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UUV FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IND:INDOLE'>IND</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1eg9|1eg9]], [[1ndo|1ndo]], [[1o7g|1o7g]], [[1o7h|1o7h]], [[1o7m|1o7m]], [[1o7n|1o7n]], [[1o7p|1o7p]], [[1o7w|1o7w]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1eg9|1eg9]], [[1ndo|1ndo]], [[1o7g|1o7g]], [[1o7h|1o7h]], [[1o7m|1o7m]], [[1o7n|1o7n]], [[1o7p|1o7p]], [[1o7w|1o7w]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uuv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uuv RCSB], [http://www.ebi.ac.uk/pdbsum/1uuv PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uuv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uuv RCSB], [http://www.ebi.ac.uk/pdbsum/1uuv PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NDOB_PSEPU NDOB_PSEPU]] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. [[http://www.uniprot.org/uniprot/NDOC_PSEPU NDOC_PSEPU]] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. The beta subunit may be responsible for the substrate specificity of the enzyme.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Naphthalene 1,2-dioxygenase]]
[[Category: Naphthalene 1,2-dioxygenase]]
[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
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[[Category: Eklund, H.]]
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[[Category: Eklund, H]]
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[[Category: Gibson, D T.]]
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[[Category: Gibson, D T]]
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[[Category: Karlsson, A.]]
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[[Category: Karlsson, A]]
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[[Category: Parales, J V.]]
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[[Category: Parales, J V]]
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[[Category: Parales, R E.]]
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[[Category: Parales, R E]]
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[[Category: Ramaswamy, S.]]
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[[Category: Ramaswamy, S]]
[[Category: Aromatic hydrocarbons catabolism]]
[[Category: Aromatic hydrocarbons catabolism]]
[[Category: Enzyme-substrate complex]]
[[Category: Enzyme-substrate complex]]
[[Category: Non-heme iron dioxygenase]]
[[Category: Non-heme iron dioxygenase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 01:34, 25 December 2014

NAPHTHALENE 1,2-DIOXYGENASE WITH NITRIC OXIDE AND INDOLE BOUND IN THE ACTIVE SITE.

1uuv, resolution 1.65Å

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