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1wy5

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wy5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WY5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wy5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WY5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ni5|1ni5]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ni5|1ni5]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wy5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wy5 RCSB], [http://www.ebi.ac.uk/pdbsum/1wy5 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wy5 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wy5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wy5 RCSB], [http://www.ebi.ac.uk/pdbsum/1wy5 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wy5 TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TILS_AQUAE TILS_AQUAE]] Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
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[[Category: Fukai, S.]]
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[[Category: Fukai, S]]
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[[Category: Ikeuchi, Y.]]
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[[Category: Ikeuchi, Y]]
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[[Category: Nakanishi, K.]]
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[[Category: Nakanishi, K]]
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[[Category: Nureki, O.]]
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[[Category: Nureki, O]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Sekine, Y.]]
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[[Category: Sekine, Y]]
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[[Category: Soma, A.]]
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[[Category: Soma, A]]
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[[Category: Suzuki, T.]]
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[[Category: Suzuki, T]]
[[Category: N-type atp-ppase]]
[[Category: N-type atp-ppase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Translation]]
[[Category: Translation]]

Revision as of 14:29, 25 December 2014

Crystal structure of isoluecyl-tRNA lysidine synthetase

1wy5, resolution 2.42Å

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