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1z7c

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z7c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z7C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z7C FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z7c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z7C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z7C FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSH1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z7c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z7c RCSB], [http://www.ebi.ac.uk/pdbsum/1z7c PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z7c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z7c RCSB], [http://www.ebi.ac.uk/pdbsum/1z7c PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CSH_HUMAN CSH_HUMAN]] Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.<ref>PMID:16546209</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kossiakoff, A A.]]
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[[Category: Kossiakoff, A A]]
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[[Category: Walsh, S T.R.]]
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[[Category: Walsh, S T.R]]
[[Category: Four-helix bundle protein]]
[[Category: Four-helix bundle protein]]
[[Category: Hormone-growth factor complex]]
[[Category: Hormone-growth factor complex]]

Revision as of 18:30, 25 December 2014

Crystal Structure of Human Placental Lactogen

1z7c, resolution 2.00Å

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