1ugv

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ugv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UGV FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ugv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UGV FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Kazusa cDNA hg04539 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Kazusa cDNA hg04539 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ugv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ugv RCSB], [http://www.ebi.ac.uk/pdbsum/1ugv PDBsum], [http://www.topsan.org/Proteins/RSGI/1ugv TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ugv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ugv RCSB], [http://www.ebi.ac.uk/pdbsum/1ugv PDBsum], [http://www.topsan.org/Proteins/RSGI/1ugv TOPSAN]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/RHG26_HUMAN RHG26_HUMAN]] Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:[http://omim.org/entry/607785 607785]]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
[[http://www.uniprot.org/uniprot/RHG26_HUMAN RHG26_HUMAN]] Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:[http://omim.org/entry/607785 607785]]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aoki, M.]]
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[[Category: Aoki, M]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi, F]]
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[[Category: Hirota, H.]]
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[[Category: Hirota, H]]
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[[Category: Inoue, K.]]
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[[Category: Inoue, K]]
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[[Category: Inoue, M.]]
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[[Category: Inoue, M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Kikuno, R.]]
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[[Category: Kikuno, R]]
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[[Category: Matsuda, T.]]
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[[Category: Matsuda, T]]
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[[Category: Matsuo, Y.]]
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[[Category: Matsuo, Y]]
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[[Category: Nagase, T.]]
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[[Category: Nagase, T]]
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[[Category: Nakayama, M.]]
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[[Category: Nakayama, M]]
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[[Category: Ohara, O.]]
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[[Category: Ohara, O]]
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[[Category: Osanai, T.]]
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[[Category: Osanai, T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Seki, E.]]
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[[Category: Seki, E]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu, M]]
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[[Category: Tanaka, A.]]
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[[Category: Tanaka, A]]
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[[Category: Terada, T.]]
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[[Category: Terada, T]]
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[[Category: Yabuki, T.]]
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[[Category: Yabuki, T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
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[[Category: Yoshida, M.]]
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[[Category: Yoshida, M]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Graf protein]]
[[Category: Graf protein]]
[[Category: Protein binding]]
[[Category: Protein binding]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 

Revision as of 13:20, 6 January 2015

Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)

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