1ypr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ypr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ypr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ypr RCSB], [http://www.ebi.ac.uk/pdbsum/1ypr PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ypr RCSB], [http://www.ebi.ac.uk/pdbsum/1ypr PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PROF_YEAST PROF_YEAST]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Almo, S C.]]
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[[Category: Almo, S C]]
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[[Category: Eads, J C.]]
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[[Category: Eads, J C]]
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[[Category: Mahoney, N M.]]
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[[Category: Mahoney, N M]]
[[Category: Actin-binding protein]]
[[Category: Actin-binding protein]]
[[Category: Cytoskeleton]]
[[Category: Cytoskeleton]]
[[Category: Profilin]]
[[Category: Profilin]]

Revision as of 14:45, 25 December 2014

SACCHAROMYCES CEREVISIAE (YEAST) PROFILIN

1ypr, resolution 2.30Å

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