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1y6d
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1y6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y6D FirstGlance]. <br> | <table><tr><td colspan='2'>[[1y6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y6D FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LuxU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 Vibrio harveyi])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LuxU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 Vibrio harveyi])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y6d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y6d RCSB], [http://www.ebi.ac.uk/pdbsum/1y6d PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y6d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y6d RCSB], [http://www.ebi.ac.uk/pdbsum/1y6d PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LUXU_VIBHA LUXU_VIBHA]] Phosphorelay protein which receives sensory signals from LuxN and LuxP and transmits them to LuxO, at low cell density. LuxN and LuxP transfer a phosphoryl group to LuxU on His-58 and this phosphoryl group is further transferred to LuxO. At high cell density, as LuxU could function to establish an equilibrium between the aspartyl-phosphate of LuxN and the aspartyl-phosphate of LuxO, LuxU transfers phosphate from LuxO to LuxN (and probably LuxP) and finally phosphate is drained from the system.<ref>PMID:9922254</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Vibrio harveyi]] | [[Category: Vibrio harveyi]] | ||
| - | [[Category: Bassler, B L | + | [[Category: Bassler, B L]] |
| - | [[Category: Cavanagh, J | + | [[Category: Cavanagh, J]] |
| - | [[Category: Kojetin, D | + | [[Category: Kojetin, D]] |
| - | [[Category: Loria, J P | + | [[Category: Loria, J P]] |
| - | [[Category: Ulrich, D L | + | [[Category: Ulrich, D L]] |
[[Category: Four-helix bundle]] | [[Category: Four-helix bundle]] | ||
[[Category: Phosphorelay]] | [[Category: Phosphorelay]] | ||
Revision as of 22:46, 25 December 2014
Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing
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