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1ze3
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ze3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZE3 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1ze3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZE3 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fimC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), fimH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), fimD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fimC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), fimH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), fimD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ze3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ze3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ze3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ze3 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ze3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ze3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ze3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ze3 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FIMC_ECOLI FIMC_ECOLI]] Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH. [[http://www.uniprot.org/uniprot/FIMD_ECOLI FIMD_ECOLI]] Involved in the export and assembly of FimA fimbrial subunits across the outer membrane. [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Bettendorff, P | + | [[Category: Bettendorff, P]] |
| - | [[Category: Capitani, G | + | [[Category: Capitani, G]] |
| - | [[Category: Eidam, O | + | [[Category: Eidam, O]] |
| - | [[Category: Glockshuber, R | + | [[Category: Glockshuber, R]] |
| - | [[Category: Grutter, M G | + | [[Category: Grutter, M G]] |
| - | [[Category: Herrmann, T | + | [[Category: Herrmann, T]] |
| - | [[Category: Horst, R | + | [[Category: Horst, R]] |
| - | [[Category: Ignatov, O | + | [[Category: Ignatov, O]] |
| - | [[Category: Jelesarov, I | + | [[Category: Jelesarov, I]] |
| - | [[Category: Nishiyama, M | + | [[Category: Nishiyama, M]] |
| - | [[Category: Vetsch, M | + | [[Category: Vetsch, M]] |
| - | [[Category: Wuthrich, K | + | [[Category: Wuthrich, K]] |
[[Category: Chaperone-structural-membrane protein complex]] | [[Category: Chaperone-structural-membrane protein complex]] | ||
[[Category: Soluble domain]] | [[Category: Soluble domain]] | ||
[[Category: Ternary complex with chaperone and pilus subunit]] | [[Category: Ternary complex with chaperone and pilus subunit]] | ||
[[Category: Usher]] | [[Category: Usher]] | ||
Revision as of 17:08, 24 December 2014
Crystal Structure of the Ternary Complex of FIMD (N-Terminal Domain) with FIMC and the Pilin Domain of FIMH
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Categories: Escherichia coli | Bettendorff, P | Capitani, G | Eidam, O | Glockshuber, R | Grutter, M G | Herrmann, T | Horst, R | Ignatov, O | Jelesarov, I | Nishiyama, M | Vetsch, M | Wuthrich, K | Chaperone-structural-membrane protein complex | Soluble domain | Ternary complex with chaperone and pilus subunit | Usher
