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2awu
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2awu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AWU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AWU FirstGlance]. <br> | <table><tr><td colspan='2'>[[2awu]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AWU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AWU FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yuq|1yuq]], [[2aww|2aww]], [[2awx|2awx]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yuq|1yuq]], [[2aww|2aww]], [[2awx|2awx]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dlg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dlg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2awu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2awu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2awu RCSB], [http://www.ebi.ac.uk/pdbsum/2awu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2awu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2awu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2awu RCSB], [http://www.ebi.ac.uk/pdbsum/2awu PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DLG1_RAT DLG1_RAT]] Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel (By similarity). May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.<ref>PMID:14960569</ref> <ref>PMID:15044483</ref> <ref>PMID:15504326</ref> <ref>PMID:19213956</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Cai, C | + | [[Category: Cai, C]] |
| - | [[Category: Goldman, A | + | [[Category: Goldman, A]] |
| - | [[Category: Keinanen, K | + | [[Category: Keinanen, K]] |
| - | [[Category: Oksanen, E | + | [[Category: Oksanen, E]] |
| - | [[Category: Ossowski, I Von | + | [[Category: Ossowski, I Von]] |
| - | [[Category: Ossowski, L Von | + | [[Category: Ossowski, L Von]] |
| - | [[Category: Sundberg, M | + | [[Category: Sundberg, M]] |
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
[[Category: Synaptic signaling]] | [[Category: Synaptic signaling]] | ||
[[Category: Trafficking protein]] | [[Category: Trafficking protein]] | ||
Revision as of 02:49, 25 December 2014
Synapse associated protein 97 PDZ2 domain variant C378G
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