2c5q
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c5q]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5Q FirstGlance]. <br> | <table><tr><td colspan='2'>[[2c5q]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5Q FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c5q RCSB], [http://www.ebi.ac.uk/pdbsum/2c5q PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c5q RCSB], [http://www.ebi.ac.uk/pdbsum/2c5q PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/YEK0_YEAST YEK0_YEAST]] Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Blondeau, K | + | [[Category: Blondeau, K]] |
| - | [[Category: Graille, M | + | [[Category: Graille, M]] |
| - | [[Category: Janin, J | + | [[Category: Janin, J]] |
| - | [[Category: Leulliot, N | + | [[Category: Leulliot, N]] |
| - | [[Category: Quevillon-Cheruel, S | + | [[Category: Quevillon-Cheruel, S]] |
| - | [[Category: Schiltz, M | + | [[Category: Schiltz, M]] |
| - | [[Category: Tilbeurgh, H Van | + | [[Category: Tilbeurgh, H Van]] |
[[Category: Pseudo-knot]] | [[Category: Pseudo-knot]] | ||
[[Category: Rraa]] | [[Category: Rraa]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Revision as of 15:24, 25 December 2014
CRYSTAL STRUCTURE OF YEAST YER010CP
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