2e2s
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2e2s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Allagelena_opulenta Allagelena opulenta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E2S FirstGlance]. <br> | <table><tr><td colspan='2'>[[2e2s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Allagelena_opulenta Allagelena opulenta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E2S FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e2s RCSB], [http://www.ebi.ac.uk/pdbsum/2e2s PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e2s RCSB], [http://www.ebi.ac.uk/pdbsum/2e2s PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TXAG_AGEOP TXAG_AGEOP]] Insect-selective toxin causing rapid but reversible paralysis in crickets. Suppresses the excitatory postsynaptic potentials evoked in lobster neuromuscular synaptic preparations, possibly by blocking the presynaptic calcium channel (Cav). Induces instantaneous reversible paralysis when injected into crickets.<ref>PMID:17644092</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Allagelena opulenta]] | [[Category: Allagelena opulenta]] | ||
| - | [[Category: Yamaji, N | + | [[Category: Yamaji, N]] |
[[Category: Cystine knot]] | [[Category: Cystine knot]] | ||
[[Category: Presynaptic calcium channel inhibitor]] | [[Category: Presynaptic calcium channel inhibitor]] | ||
[[Category: Toxin]] | [[Category: Toxin]] | ||
Revision as of 21:10, 25 December 2014
Solution structure of agelenin, an insecticidal peptide from the venom of Agelena opulenta
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