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2as8

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2as8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AS8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2as8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dermatophagoides_pteronyssinus Dermatophagoides pteronyssinus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AS8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2as8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2as8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2as8 RCSB], [http://www.ebi.ac.uk/pdbsum/2as8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2as8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2as8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2as8 RCSB], [http://www.ebi.ac.uk/pdbsum/2as8 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DERP1_DERPT DERP1_DERPT]] Thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Dermatophagoides pteronyssinus]]
[[Category: Dermatophagoides pteronyssinus]]
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[[Category: Carlier, V.]]
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[[Category: Carlier, V]]
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[[Category: Halleux, S de.]]
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[[Category: Halleux, S de]]
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[[Category: Jacquemin, M.]]
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[[Category: Jacquemin, M]]
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[[Category: Saint-Remy, J M.]]
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[[Category: Saint-Remy, J M]]
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[[Category: Stura, E.]]
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[[Category: Stura, E]]
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[[Category: VanderElst, L.]]
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[[Category: VanderElst, L]]
[[Category: Cysteine proteinase fold]]
[[Category: Cysteine proteinase fold]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 21:23, 25 December 2014

Crystal structure of mature and fully active Der p 1 allergen

2as8, resolution 1.95Å

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