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2edf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2edf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EDF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2edf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EDF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OBSCN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OBSCN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2edf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2edf RCSB], [http://www.ebi.ac.uk/pdbsum/2edf PDBsum], [http://www.topsan.org/Proteins/RSGI/2edf TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2edf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2edf RCSB], [http://www.ebi.ac.uk/pdbsum/2edf PDBsum], [http://www.topsan.org/Proteins/RSGI/2edf TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/OBSCN_HUMAN OBSCN_HUMAN]] Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle. Isoform 3 together with ANK1 isoform Mu17/Ank1.5 may provide a molecular link between the sarcoplasmic reticulum and myofibrils.<ref>PMID:11448995</ref> <ref>PMID:16205939</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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*[[Group:MUZIC:Obscurin|MUZIC:Obscurin]]
*[[Group:MUZIC:Obscurin|MUZIC:Obscurin]]
*[[Obscurin|Obscurin]]
*[[Obscurin|Obscurin]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi, F]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Wakabayashi, M.]]
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[[Category: Wakabayashi, M]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
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[[Category: Yoshida, M.]]
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[[Category: Yoshida, M]]
[[Category: Beta-sandwich]]
[[Category: Beta-sandwich]]
[[Category: Contractile protein]]
[[Category: Contractile protein]]
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[[Category: Obscurin-myosin light chain kinase]]
[[Category: Obscurin-myosin light chain kinase]]
[[Category: Obscurin-rhogef]]
[[Category: Obscurin-rhogef]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 

Revision as of 15:09, 24 December 2014

Solution structure of the second ig-like domain(2826-2915) from human Obscurin

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