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2b6o
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2b6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B6O FirstGlance]. <br> | <table><tr><td colspan='2'>[[2b6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B6O FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sor|1sor]], [[2b6p|2b6p]], [[1ymg|1ymg]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sor|1sor]], [[2b6p|2b6p]], [[1ymg|1ymg]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b6o RCSB], [http://www.ebi.ac.uk/pdbsum/2b6o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b6o RCSB], [http://www.ebi.ac.uk/pdbsum/2b6o PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MIP_SHEEP MIP_SHEEP]] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:15141214</ref> <ref>PMID:15351655</ref> <ref>PMID:20389283</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Ovis aries]] | [[Category: Ovis aries]] | ||
| - | [[Category: Cheng, Y | + | [[Category: Cheng, Y]] |
| - | [[Category: Fujiyoshi, Y | + | [[Category: Fujiyoshi, Y]] |
| - | [[Category: Gonen, T | + | [[Category: Gonen, T]] |
| - | [[Category: Harrison, S C | + | [[Category: Harrison, S C]] |
| - | [[Category: Hiroaki, Y | + | [[Category: Hiroaki, Y]] |
| - | [[Category: Sliz, P | + | [[Category: Sliz, P]] |
| - | [[Category: Walz, T | + | [[Category: Walz, T]] |
[[Category: Aqp0]] | [[Category: Aqp0]] | ||
[[Category: Aquaporin-0 junction]] | [[Category: Aquaporin-0 junction]] | ||
Revision as of 03:32, 25 December 2014
electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) at 1.9A resolution, in a closed pore state
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