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2ecg

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ecg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ECG FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ecg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ECG FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BIRC4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BIRC4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ecg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ecg RCSB], [http://www.ebi.ac.uk/pdbsum/2ecg PDBsum], [http://www.topsan.org/Proteins/RSGI/2ecg TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ecg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ecg RCSB], [http://www.ebi.ac.uk/pdbsum/2ecg PDBsum], [http://www.topsan.org/Proteins/RSGI/2ecg TOPSAN]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/BIRC4_HUMAN BIRC4_HUMAN]] Defects in XIAP are the cause of lymphoproliferative syndrome X-linked type 2 (XLP2) [MIM:[http://omim.org/entry/300635 300635]]. XLP is a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus (EBV). Symptoms include severe or fatal mononucleosis, acquired hypogammaglobulinemia, pancytopenia and malignant lymphoma.<ref>PMID:17080092</ref>
[[http://www.uniprot.org/uniprot/BIRC4_HUMAN BIRC4_HUMAN]] Defects in XIAP are the cause of lymphoproliferative syndrome X-linked type 2 (XLP2) [MIM:[http://omim.org/entry/300635 300635]]. XLP is a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus (EBV). Symptoms include severe or fatal mononucleosis, acquired hypogammaglobulinemia, pancytopenia and malignant lymphoma.<ref>PMID:17080092</ref>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Harada, T.]]
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[[Category: Harada, T]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba, S]]
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[[Category: Miyamoto, K.]]
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[[Category: Miyamoto, K]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Sato, M.]]
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[[Category: Sato, M]]
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[[Category: Watanabe, S.]]
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[[Category: Watanabe, S]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Baculoviral iap repeat-containing protein 4]]
[[Category: Baculoviral iap repeat-containing protein 4]]
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[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Ring domian]]
[[Category: Ring domian]]
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Zinc-binding domain]]
[[Category: Zinc-binding domain]]

Revision as of 18:42, 15 January 2015

Solution structure of the ring domain of the Baculoviral IAP repeat-containing protein 4 from Homo sapiens

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