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2dhr
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2dhr]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DHR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DHR FirstGlance]. <br> | <table><tr><td colspan='2'>[[2dhr]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DHR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DHR FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ixz|1ixz]], [[1iy0|1iy0]], [[1iy1|1iy1]], [[1iy2|1iy2]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ixz|1ixz]], [[1iy0|1iy0]], [[1iy1|1iy1]], [[1iy2|1iy2]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dhr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dhr RCSB], [http://www.ebi.ac.uk/pdbsum/2dhr PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dhr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dhr RCSB], [http://www.ebi.ac.uk/pdbsum/2dhr PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q9LCZ4_THETH Q9LCZ4_THETH]] Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity).[HAMAP-Rule:MF_01458] Degrades preferentially unfolded substrates in a processive, ATP-dependent manner, usually after hydrophobic residues.[HAMAP-Rule:MF_01458] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Morikawa, K | + | [[Category: Morikawa, K]] |
| - | [[Category: Niwa, H | + | [[Category: Niwa, H]] |
| - | [[Category: Suno, R | + | [[Category: Suno, R]] |
| - | [[Category: Tsuchiya, D | + | [[Category: Tsuchiya, D]] |
| - | [[Category: Yoshida, M | + | [[Category: Yoshida, M]] |
| - | [[Category: Zhang, X | + | [[Category: Zhang, X]] |
[[Category: Aaa+ protein]] | [[Category: Aaa+ protein]] | ||
[[Category: Hexameric zn metalloprotease]] | [[Category: Hexameric zn metalloprotease]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 20:21, 25 December 2014
Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L)
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