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2bx6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bx6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BX6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2bx6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BX6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bx6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bx6 RCSB], [http://www.ebi.ac.uk/pdbsum/2bx6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bx6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bx6 RCSB], [http://www.ebi.ac.uk/pdbsum/2bx6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/XRP2_HUMAN XRP2_HUMAN]] Defects in RP2 are the cause of retinitis pigmentosa type 2 (RP2) [MIM:[http://omim.org/entry/312600 312600]]; also known as X-linked retinitis pigmentosa 2 (XLRP-2). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.<ref>PMID:11847227</ref> <ref>PMID:16472755</ref> <ref>PMID:10942419</ref> <ref>PMID:9697692</ref> <ref>PMID:10090907</ref> <ref>PMID:10520237</ref> <ref>PMID:10634633</ref> <ref>PMID:10937588</ref> <ref>PMID:11462235</ref> <ref>PMID:11992260</ref> <ref>PMID:14564670</ref> <ref>PMID:12657579</ref> <ref>PMID:22334370</ref> | [[http://www.uniprot.org/uniprot/XRP2_HUMAN XRP2_HUMAN]] Defects in RP2 are the cause of retinitis pigmentosa type 2 (RP2) [MIM:[http://omim.org/entry/312600 312600]]; also known as X-linked retinitis pigmentosa 2 (XLRP-2). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.<ref>PMID:11847227</ref> <ref>PMID:16472755</ref> <ref>PMID:10942419</ref> <ref>PMID:9697692</ref> <ref>PMID:10090907</ref> <ref>PMID:10520237</ref> <ref>PMID:10634633</ref> <ref>PMID:10937588</ref> <ref>PMID:11462235</ref> <ref>PMID:11992260</ref> <ref>PMID:14564670</ref> <ref>PMID:12657579</ref> <ref>PMID:22334370</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Kuhnel, K | + | [[Category: Kuhnel, K]] |
| - | [[Category: Schlichting, I | + | [[Category: Schlichting, I]] |
| - | [[Category: Veltel, S | + | [[Category: Veltel, S]] |
| - | [[Category: Wittinghofer, A | + | [[Category: Wittinghofer, A]] |
[[Category: Retinitis pigmentosa]] | [[Category: Retinitis pigmentosa]] | ||
[[Category: Sensory transduction]] | [[Category: Sensory transduction]] | ||
[[Category: Transduction protein]] | [[Category: Transduction protein]] | ||
[[Category: Vision]] | [[Category: Vision]] | ||
Revision as of 17:09, 15 January 2015
CRYSTAL STRUCTURE OF THE HUMAN RETINITIS PIGMENTOSA PROTEIN 2 (RP2)
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