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2arj

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2arj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ARJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ARJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2arj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ARJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ARJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nez|1nez]], [[1bqh|1bqh]], [[1akj|1akj]], [[1cd8|1cd8]], [[1q69|1q69]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nez|1nez]], [[1bqh|1bqh]], [[1akj|1akj]], [[1cd8|1cd8]], [[1q69|1q69]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd8a, Lyt-2, Lyt2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd8a, Lyt-2, Lyt2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2arj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2arj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2arj RCSB], [http://www.ebi.ac.uk/pdbsum/2arj PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2arj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2arj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2arj RCSB], [http://www.ebi.ac.uk/pdbsum/2arj PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CD8A_MOUSE CD8A_MOUSE]] Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Dwek, R A.]]
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[[Category: Dwek, R A]]
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[[Category: Rudd, P M.]]
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[[Category: Rudd, P M]]
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[[Category: Shore, D A.]]
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[[Category: Shore, D A]]
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[[Category: Teyton, L.]]
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[[Category: Teyton, L]]
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[[Category: Wilson, I A.]]
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[[Category: Wilson, I A]]
[[Category: Antibody fab]]
[[Category: Antibody fab]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Immunoglobulin domain]]
[[Category: Immunoglobulin domain]]
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]

Revision as of 22:34, 25 December 2014

CD8alpha-alpha in complex with YTS 105.18 Fab

2arj, resolution 2.88Å

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