2ecb
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ecb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2djo 2djo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ECB FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ecb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2djo 2djo]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ECB FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZHX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZHX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ecb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ecb RCSB], [http://www.ebi.ac.uk/pdbsum/2ecb PDBsum], [http://www.topsan.org/Proteins/RSGI/2ecb TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ecb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ecb RCSB], [http://www.ebi.ac.uk/pdbsum/2ecb PDBsum], [http://www.topsan.org/Proteins/RSGI/2ecb TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ZHX1_HUMAN ZHX1_HUMAN]] Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.<ref>PMID:12237128</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Inoue, M | + | [[Category: Inoue, M]] |
| - | [[Category: Kigawa, T | + | [[Category: Kigawa, T]] |
| - | [[Category: Koshiba, S | + | [[Category: Koshiba, S]] |
| - | [[Category: Ohnishi, S | + | [[Category: Ohnishi, S]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Saito, K | + | [[Category: Saito, K]] |
| - | [[Category: Sasagawa, A | + | [[Category: Sasagawa, A]] |
| - | [[Category: Tochio, N | + | [[Category: Tochio, N]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Homeobox domain]] | [[Category: Homeobox domain]] | ||
[[Category: National project on protein structural and functional analyse]] | [[Category: National project on protein structural and functional analyse]] | ||
[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription factor]] | [[Category: Transcription factor]] | ||
[[Category: Zinc fingers and homeoboxes protein]] | [[Category: Zinc fingers and homeoboxes protein]] | ||
Revision as of 21:56, 24 December 2014
The solution structure of the third homeobox domain of human zinc fingers and homeoboxes protein
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Categories: Homo sapiens | Inoue, M | Kigawa, T | Koshiba, S | Ohnishi, S | Structural genomic | Saito, K | Sasagawa, A | Tochio, N | Yokoyama, S | Homeobox domain | National project on protein structural and functional analyse | Nppsfa | Rsgi | Transcription | Transcription factor | Zinc fingers and homeoboxes protein
