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2gat
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2gat]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAT FirstGlance]. <br> | <table><tr><td colspan='2'>[[2gat]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAT FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gat|3gat]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gat|3gat]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gat OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gat RCSB], [http://www.ebi.ac.uk/pdbsum/2gat PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gat OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gat RCSB], [http://www.ebi.ac.uk/pdbsum/2gat PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GATA1_CHICK GATA1_CHICK]] Transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| - | [[Category: Clore, G M | + | [[Category: Clore, G M]] |
| - | [[Category: Gronenborn, A M | + | [[Category: Gronenborn, A M]] |
| - | [[Category: Omichinski, J G | + | [[Category: Omichinski, J G]] |
| - | [[Category: Starich, M | + | [[Category: Starich, M]] |
| - | [[Category: Tjandra, N | + | [[Category: Tjandra, N]] |
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
[[Category: Transcription factor]] | [[Category: Transcription factor]] | ||
[[Category: Transcription-dna complex]] | [[Category: Transcription-dna complex]] | ||
[[Category: Zinc binding domain]] | [[Category: Zinc binding domain]] | ||
Revision as of 14:45, 24 December 2014
SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE
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