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2j7t
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2j7t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J7T FirstGlance]. <br> | <table><tr><td colspan='2'>[[2j7t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J7T FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=274:(3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE'>274</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=274:(3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE'>274</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j7t RCSB], [http://www.ebi.ac.uk/pdbsum/2j7t PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j7t RCSB], [http://www.ebi.ac.uk/pdbsum/2j7t PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Das, S | + | [[Category: Das, S]] |
| - | [[Category: Debreczeni, J | + | [[Category: Debreczeni, J]] |
| - | [[Category: Delft, F Von | + | [[Category: Delft, F Von]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Eswaran, J | + | [[Category: Eswaran, J]] |
| - | [[Category: Fedorov, O | + | [[Category: Fedorov, O]] |
| - | [[Category: Gorrec, F | + | [[Category: Gorrec, F]] |
| - | [[Category: Knapp, S | + | [[Category: Knapp, S]] |
| - | [[Category: Papagrigoriou, E | + | [[Category: Papagrigoriou, E]] |
| - | [[Category: Pike, A C.W | + | [[Category: Pike, A C.W]] |
| - | [[Category: Rellos, P | + | [[Category: Rellos, P]] |
| - | [[Category: Savitsky, P | + | [[Category: Savitsky, P]] |
| - | [[Category: Sobott, F | + | [[Category: Sobott, F]] |
| - | [[Category: Sundstrom, M | + | [[Category: Sundstrom, M]] |
| - | [[Category: Turnbull, A P | + | [[Category: Turnbull, A P]] |
| - | [[Category: Ugochukwa, E | + | [[Category: Ugochukwa, E]] |
| - | [[Category: Umeano, C C | + | [[Category: Umeano, C C]] |
| - | [[Category: Watt, S | + | [[Category: Watt, S]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell cycle progression]] | [[Category: Cell cycle progression]] | ||
Revision as of 14:22, 19 January 2015
CRYSTAL STRUCTURE OF HUMAN SERINE THREONINE KINASE-10 BOUND TO SU11274
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Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Das, S | Debreczeni, J | Delft, F Von | Edwards, A | Eswaran, J | Fedorov, O | Gorrec, F | Knapp, S | Papagrigoriou, E | Pike, A C.W | Rellos, P | Savitsky, P | Sobott, F | Sundstrom, M | Turnbull, A P | Ugochukwa, E | Umeano, C C | Watt, S | Weigelt, J | Atp-binding | Cell cycle progression | Disease mutation | Kinase | Nucleotide- binding | Phosphorylation | Serine/threonine- protein kinase | Transferase
