2jpe
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jpe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JPE FirstGlance]. <br> | <table><tr><td colspan='2'>[[2jpe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JPE FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ppp1r8, Nipp1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ppp1r8, Nipp1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jpe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jpe RCSB], [http://www.ebi.ac.uk/pdbsum/2jpe PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jpe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jpe RCSB], [http://www.ebi.ac.uk/pdbsum/2jpe PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PP1R8_MOUSE PP1R8_MOUSE]] Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Essential for cell proliferation and early embryonic development.<ref>PMID:15501817</ref> <ref>PMID:15199142</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Fujioka, Y | + | [[Category: Fujioka, Y]] |
| - | [[Category: Inagaki, F | + | [[Category: Inagaki, F]] |
| - | [[Category: Kikuchi, K | + | [[Category: Kikuchi, K]] |
| - | [[Category: Kumeta, H | + | [[Category: Kumeta, H]] |
| - | [[Category: Ogura, K | + | [[Category: Ogura, K]] |
| - | [[Category: Tanuma, N | + | [[Category: Tanuma, N]] |
[[Category: Fha domain]] | [[Category: Fha domain]] | ||
[[Category: Mrna splicing]] | [[Category: Mrna splicing]] | ||
[[Category: Nipp1]] | [[Category: Nipp1]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 13:51, 25 December 2014
FHA domain of NIPP1
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Categories: Mus musculus | Fujioka, Y | Inagaki, F | Kikuchi, K | Kumeta, H | Ogura, K | Tanuma, N | Fha domain | Mrna splicing | Nipp1 | Transcription
