2hp4
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2hp4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HP4 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2hp4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HP4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HP4 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hp4 RCSB], [http://www.ebi.ac.uk/pdbsum/2hp4 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hp4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hp4 RCSB], [http://www.ebi.ac.uk/pdbsum/2hp4 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/CD8A_HUMAN CD8A_HUMAN]] Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:[http://omim.org/entry/608957 608957]]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. | [[http://www.uniprot.org/uniprot/CD8A_HUMAN CD8A_HUMAN]] Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:[http://omim.org/entry/608957 608957]]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Boulter, J M | + | [[Category: Boulter, J M]] |
| - | [[Category: Cole, D K | + | [[Category: Cole, D K]] |
| - | [[Category: Gao, G F | + | [[Category: Gao, G F]] |
| - | [[Category: Glick, M | + | [[Category: Glick, M]] |
| - | [[Category: Jakobsen, B K | + | [[Category: Jakobsen, B K]] |
| - | [[Category: Rizkallah, P J | + | [[Category: Rizkallah, P J]] |
[[Category: Cd8]] | [[Category: Cd8]] | ||
[[Category: Co-receptor]] | [[Category: Co-receptor]] | ||
Revision as of 09:32, 16 January 2015
Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor
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