2gle

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gle]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GLE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GLE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gle]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GLE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GLE FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gle OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gle RCSB], [http://www.ebi.ac.uk/pdbsum/2gle PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gle OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gle RCSB], [http://www.ebi.ac.uk/pdbsum/2gle PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NEB1_RAT NEB1_RAT]] Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Hudak, J.]]
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[[Category: Hudak, J]]
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[[Category: Ju, T.]]
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[[Category: Ju, T]]
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[[Category: Peti, W.]]
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[[Category: Peti, W]]
[[Category: Protein binding]]
[[Category: Protein binding]]
[[Category: Protein protein interaction]]
[[Category: Protein protein interaction]]
[[Category: Sam domain]]
[[Category: Sam domain]]
[[Category: Scaffold]]
[[Category: Scaffold]]

Revision as of 10:26, 25 December 2014

Solution structure of neurabin SAM domain

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