2htm

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2htm]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HTM FirstGlance]. <br>
<table><tr><td colspan='2'>[[2htm]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HTM FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2htm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2htm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2htm RCSB], [http://www.ebi.ac.uk/pdbsum/2htm PDBsum], [http://www.topsan.org/Proteins/RSGI/2htm TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2htm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2htm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2htm RCSB], [http://www.ebi.ac.uk/pdbsum/2htm PDBsum], [http://www.topsan.org/Proteins/RSGI/2htm TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/THIG_THET8 THIG_THET8]] Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Kunishima, N.]]
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[[Category: Kunishima, N]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Sugahara, M.]]
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[[Category: Sugahara, M]]
[[Category: Biosynthetic protein]]
[[Category: Biosynthetic protein]]
[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Thermus thermophilus hb8]]
[[Category: Thermus thermophilus hb8]]
[[Category: Thiamin biosynthesis]]
[[Category: Thiamin biosynthesis]]
[[Category: Thig]]
[[Category: Thig]]

Revision as of 16:19, 24 December 2014

Crystal structure of TTHA0676 from Thermus thermophilus HB8

2htm, resolution 2.30Å

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