2iyc
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2iyc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IYC FirstGlance]. <br> | <table><tr><td colspan='2'>[[2iyc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IYC FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ckg|2ckg]], [[2ckh|2ckh]], [[2iy0|2iy0]], [[2iy1|2iy1]], [[2iyd|2iyd]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ckg|2ckg]], [[2ckh|2ckh]], [[2iy0|2iy0]], [[2iy1|2iy1]], [[2iyd|2iyd]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iyc RCSB], [http://www.ebi.ac.uk/pdbsum/2iyc PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iyc RCSB], [http://www.ebi.ac.uk/pdbsum/2iyc PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SENP1_HUMAN SENP1_HUMAN]] Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.<ref>PMID:10652325</ref> <ref>PMID:15199155</ref> <ref>PMID:16253240</ref> <ref>PMID:16553580</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Dong, C | + | [[Category: Dong, C]] |
| - | [[Category: Naismith, J H | + | [[Category: Naismith, J H]] |
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Nuclear protein]] | [[Category: Nuclear protein]] | ||
Revision as of 12:38, 25 December 2014
SENP1 NATIVE STRUCTURE
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