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2jkg
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jkg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JKG FirstGlance]. <br> | <table><tr><td colspan='2'>[[2jkg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JKG FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jkf|2jkf]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jkf|2jkf]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jkg RCSB], [http://www.ebi.ac.uk/pdbsum/2jkg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jkg RCSB], [http://www.ebi.ac.uk/pdbsum/2jkg PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PROF_PLAF7 PROF_PLAF7]] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers (By similarity).[UniProtKB:P86294] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
| - | [[Category: Ganter, M | + | [[Category: Ganter, M]] |
| - | [[Category: Kursula, I | + | [[Category: Kursula, I]] |
| - | [[Category: Kursula, P | + | [[Category: Kursula, P]] |
| - | [[Category: Matuschewski, K | + | [[Category: Matuschewski, K]] |
| - | [[Category: Panjikar, S | + | [[Category: Panjikar, S]] |
| - | [[Category: Schueler, H | + | [[Category: Schueler, H]] |
[[Category: Cytoskeleton]] | [[Category: Cytoskeleton]] | ||
[[Category: Malaria]] | [[Category: Malaria]] | ||
[[Category: Proline-rich ligand]] | [[Category: Proline-rich ligand]] | ||
[[Category: Protein-binding]] | [[Category: Protein-binding]] | ||
Revision as of 16:28, 24 December 2014
PLASMODIUM FALCIPARUM PROFILIN
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